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New paper in PLOS Biology


New paper in Nature Communications


New paper in PLOS Biology
  1. Cansizoglu, M. F., & Toprak, E. (2017). Fighting against evolution of antibiotic resistance by utilizing evolvable antimicrobial drugs. Current Genetics, 1-4. doi: 10.1007/s00294-017-0703-x

  2. Abdizadeh, H., Tamer, Y. T., Acar, O., Toprak, E., Atilgan, A. R., & Atilgan, C. (2017). Increased substrate affinity in the Escherichia coli L28R dihydrofolate reductase mutant causes trimethoprim resistance. Physical Chemistry Chemical Physics, 19(18), 11416-11428. doi: 10.1039/c7cp01458a

  3. Ayhan, D.H., Tamer, Y.T., Akbar, M., Bailey, S.M., Wong, M., Daly, S.M., Greenberg, D.E. and Toprak, E., 2016. Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy. PLoS Biol, 14(9), p.e1002552.doi: 10.1371/journal.pbio.1002552

  4. Okumus, B., Landgraf, D., Lai, G.C., Bakhsi, S., Arias-Castro, J.C., Yildiz, S., Huh, D., Fernandez-Lopez, R., Peterson, C.N., Toprak, E. and El Karoui, M., 2016. Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells. Nature communications, 7. doi:10.1038/ncomms11641

  5. Chevereau, G., Dravecká, M., Batur, T., Guvenek, A., Ayhan, D.H., Toprak, E. and Bollenbach, T., 2015. Quantifying the Determinants of Evolutionary Dynamics Leading to Drug Resistance. PLoS Biol, 13(11), p.e1002299. doi:10.1371/journal.pbio.1002299

  6. Palmer, A.C., Toprak, E., Baym, M., Kim, S., Veres, A., Bershtein, S. and Kishony, R., 2015. Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes. Nature communications, 6. doi:10.1038/ncomms8385

  7. Oz, T., Guvenek, A., Yildiz, S., Karaboga, E., Tamer, Y.T., Mumcuyan, N., Ozan, V.B., Senturk, G.H., Cokol, M., Yeh, P., Toprak, E.*, “Selection strength contributes to the complexity of antibiotic resistance evolution”, Molecular Biology and Evolution, (Published online: June 24, 2014, * corresponding author). doi:10.1093/molbev/msu191

  8. B. Okumus, S. Yildiz, E. Toprak*, “Fluidic and microfluidic tools for quantitative systems biology”, Current Opinion in Biotechnology, 2014, * corresponding author. doi:10.1016/j.copbio.2013.08.016

  9. E. Toprak*, A. Veres, S. Yildiz, J.M. Pedraza, R. Chait, J. Paulsson, R. Kishony*, “Building a Morbidostat: An automated high-throughput fluidic system for studying bacterial drug resistance in dynamically sustained drug environments”, Nature Protocols, 2013; E.T. and R.K. are corresponding authors). doi:10.1038/nprot.2013.021

  10. E. Toprak, A. Veres, J.B. Michel, R. Chait, D.L. Hartl, R. Kishony, “Evolutionary paths to strong antibiotic resistance under dynamically sustained drug stress”, Nature Genetics, 2012. doi:10.1038/ng.1034

  11. E. Toprak, C. Kural, P. R. Selvin, "Super-accuracy and super-resolution getting around the diffraction limit.", Methods in Enzymology, 2010.doi: 10.1016/S0076-6879(10)75001-1

  12. E. Toprak, A. Yildiz, M.T. Hoffman, S.S. Rosenfeld, P.R. Selvin, “Why kinesin is so processive”, PNAS, 2009doi: 10.1073/pnas.0808396106

  13. J. G. Reifenberger, E. Toprak, H. Kim, D. Safer, H.L. Sweeney, P.R. Selvin, “Myosin VI undergoes a 180° Power stroke implying an uncoupling of the front lever arm”, PNAS, 2009, (J.G.R. and E.T. contributed equally).doi: 10.1073/pnas.0900005106

  14. E. Toprak, H. Balci, B.H. Blehm, P.R. Selvin, “3D Particle Tracking via Bifocal Imaging”, Nano Letters, 2007.PMID: 17583964

  15. E. Toprak and P.R. Selvin, “New Fluorescent Tools for Watching Nanometer-Scale Conformational Changes of Single Molecules”, Annual Review of Biophysics and Biomolecular Structure, 2007.PMID: 17298239

  16. H. Park, E. Toprak, P. R. Selvin, “Single-molecule fluorescence to study molecular motors”, Quarterly Reviews of Biophysics, 2007.PMID: 17666122

  17. P.R. Selvin, T. Lougheed, M.T. Hoffman, H. Park, H. Balci, B.H. Blehm, E. Toprak, “In vitro & in vivo FIONA and other acronyms for watching molecular motors walk”, Single Molecules: A Laboratory Manual. Cold Spring Harbor Press. Edited by Selvin, P.R., Taekjip Ha, Univ. of Illinois, 2007.doi: 10.1101/pdb.top27

  18. J. Enderlein, E. Toprak, P. R. Selvin, “Polarization effect on position accuracy of fluorophore localization”, Optics Express, 2006.PMID: 19529183

  19. E. Toprak, J. Enderlein, S. Syed, S.A. McKinney, R.G. Petschek, T. Ha, Y.E. Goldman, P.R. Selvin, “Defocused Orientation and Position Imaging of Myosin V”, PNAS, 2006.PMID: 16614073

  20. E. Toprak and O.T. Turgut, “Large N limit of SO(N) Scalar Gauge Theory”, Journal of Mathematical Physics, 2002.

  21. E. Toprak and O.T. Turgut, “Large N limit of SO(N) Gauge Theory of Fermions and Bosons”, Journal of Mathematical Physics, 2002